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Alcohol

GABA-A dynamics, Kudzu, PAWS, medical safety.

10 articles

GABA Supplementation During Alcohol Recovery: What It Can and Cannot Do

The DRY protocol includes supplemental GABA. Understanding why-and the significant pharmacological limitations of oral GABA-requires a careful look at the blood-brain barrier.

Mar 16, 20253 min read

L-Glutamine and the Gut-Brain Axis in Alcohol Recovery

Alcohol damages intestinal lining, increasing gut permeability and driving systemic inflammation that reaches the brain. L-Glutamine is the primary intestinal repair amino acid.

Mar 9, 20253 min read

Alcohol and the Brain: What Heavy Use Actually Does and What Recovers

Heavy alcohol use produces measurable brain volume loss, white matter damage, and neurotransmitter disruption. Most is reversible with sustained abstinence, but the timeline is longer than expected.

Mar 2, 20253 min read

NAC and Liver Protection: Why It's in the DRY Protocol

NAC is the clinical treatment for acetaminophen-induced liver failure. It works through glutathione synthesis. Alcohol produces similar oxidative liver stress through different mechanisms.

Feb 23, 20253 min read

Social Drinking Culture and Cessation: The Unique Challenge of Alcohol

Every other substance has become socially marginal. Alcohol is built into networking events, weddings, restaurants, and professional culture. Cessation requires a social strategy.

Feb 16, 20254 min read

Thiamine and Wernicke's Encephalopathy: The Most Medically Critical Part of the DRY Protocol

Alcohol impairs thiamine absorption and depletes stores. The result, if severe, is irreversible neurological damage. This is the medical emergency hidden inside alcohol withdrawal.

Feb 9, 20253 min read

The DRY Protocol: Week by Week

An honest, mechanism-based account of alcohol cessation over 8 weeks, what the DRY protocol is doing at each stage, and what to genuinely expect.

Feb 2, 20253 min read

PAWS: The Post-Acute Withdrawal That Derails Long-Term Recovery

Post-acute withdrawal syndrome can last months to years in heavy alcohol users. Mood instability, cognitive fog, sleep disruption, and craving recur episodically long after acute withdrawal ends.

Jan 25, 20253 min read

Kudzu Root: Three Clinical Trials and Why It Works

Pueraria lobata isoflavones modulate dopaminergic and serotonergic systems to reduce the reward value of alcohol. Three published human clinical trials. Nearly invisible in the US market.

Jan 18, 20253 min read

GABA and NMDA: The Biochemistry of Alcohol Withdrawal

Alcohol withdrawal is the only common substance withdrawal that can kill you. Understanding why requires understanding what chronic alcohol does to GABA-A and NMDA receptors simultaneously.

Jan 10, 20254 min read